The Locust continued to grow their civilization - developing a military, culture, and religion known as the Trinity of Worms. Queen Myrrah led her people deeper into the caverns of Mount Kadar where they began to build their own civilization, Nexus. Myrrah's sympathy for her "children" caused her to lead the Locust, as their Queen, to slaughter the scientists and escape the facility. The work there led to the creation of the Locust Horde by combining the embryonic stem cells of Myrrah, a child born with a genetic immunity to Imulsion, and Sire DNA. Samson and his research was relocated to a secret facility inside Mount Kadar. Before the eventual shutdown of the facility, Dr. The children were mutated by the Imulsion and DNA of indigenous creatures from the Hollow, resulting in chimeras known as the Sires. Doctor Niles Samson led experiments on children of Imulsion-poisoned miners in order to find a cure for Rustlung. The Locust Horde were created by the Coalition of Ordered Governments during the Pendulum Wars and originated from a genetic research project at the New Hope Research Facility. The Locust Horde, often called Grubs by Serans, were a race of mutated humans that established their civilization in the subterranean regions of Sera, known as the Hollow. Aside from that, I'm afraid." -An unidentified human scientist dubbing the name of the Locust Horde We've tagged them Locust since this degree of death has only been seen in times of plague. as the Swarm " Frankly, other than the fact that they want to kill every man, woman and child out there, we know nothing about them.